What is the terpene Caryophyllene found in cannabis?

Top Answer

Medical Jane

Last updated: May 30th, 2016

Caryophyllene (or β–caryophyllene) is a sesquiterpene found in many plants such as Thai basils, cloves, cinnamon leaves and black pepper, and in minor quantities in lavender. It creates woody, spicy aromas with a similar flavor palate. Caryophyllene is used especially in chewing gum when combined with other spicy mixtures or citrus flavorings.

Caryophyllene is the only terpene known to interact with the endocannabinoid system (CB2). Research shows that β–caryophyllene selectively binds to the CB2 receptor and that it is a functional CB2 agonist. Further, β–caryophyllene was identified as a functional non-psychoactive CB2 receptor ligand in foodstuff and as a macrocyclic anti-inflammatory cannabinoid in cannabis.

Click here to learn more about Caryophyllene and other terpenes commonly found in cannabis.

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