Last updated: June 1st, 2016
CB1 is predominantly located in the nervous system, connective tissues, gonads, glands, and organs. CB1 is not found in the medulla oblongata (the part of the brain stem responsible for respiratory and cardiovascular functions). Current research shows that THC is specially keyed to the CB1 receptor site, making it responsible for the euphoric effects most associated with cannabis. When THC is present in the CB1, feelings of pain are reduced.
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